2013

articolo postato il: 2013-04-30 12:14:42

Reduction of conformational mobility and aggregation in W60G β2 -microglobulin: assessment by 15 N NMR relaxation.

Gümral D, Fogolari F, Corazza A, Viglino P, Giorgetti S, Stoppini M, Bellotti V, Esposito G.

Magn Reson Chem. 2013 Oct 18. doi: 10.1002/mrc.4018.

 

Structure, folding dynamics and amyloidogenesis of Asp76Asn β2-microglobulin: roles of shear flow, hydrophobic surfaces and α crystallin.

Mangione PP, Esposito G, Relini A, Raimondi S, Porcari R, Giorgetti S, Corazza A, Fogolari F, Penco A, Goto Y, Lee YH, Yagi H, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Chiti F, Rolandi R, Taylor GW, Pepys MB, Stoppini M, Bellotti V.

J Biol Chem. 2013 Oct 25;288(43):30917-30. doi: 10.1074/jbc.M113.498857.

 

Structure of an early native-like intermediate of β2-microglobulin amyloidogenesis.

Vanderhaegen S, Fislage M, Domanska K, Versées W, Pardon E, Bellotti V, Steyaert J.

Protein Sci. 2013 Oct;22(10):1349-57. doi: 10.1002/pro.2321

 

Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis.

Montagna G, Cazzulani B, Obici L, Uggetti C, Giorgetti S, Porcari R, Ruggiero R, Mangione PP, Brambilla M, Lucchetti J, Guiso G, Gobbi M, Merlini G, Salmona M, Stoppini M, Villa G, Bellotti V.

Amyloid. 2013 Sep;20(3):173-8. doi: 10.3109/13506129.2013.803463.

 

Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry. αB-Crystallin dissociates β2-microglobulin oligomers.

Esposito G, Garvey M, Alverdi V, Pettirossi F, Corazza A, Fogolari F, Polano M, Mangione PP, Giorgetti S, Stoppini M, Rekas A, Bellotti V, Heck AJ, Carver JA.

J Biol Chem. 2013 Jun 14;288(24):17844-58. doi: 10.1074/jbc.M112.448639

 

Pathogenetic mechanisms of amyloid A amyloidosis.

Simons JP, Al-Shawi R, Ellmerich S, Speck I, Aslam S, Hutchinson WL, Mangione PP, Disterer P, Gilbertson JA, Hunt T, Millar DJ, Minogue S, Bodin K, Pepys MB, Hawkins PN.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16115-20. doi: 10.1073/pnas.1306621110.

 

Single Point Mutations Induce a Switch in the Molecular Mechanism of the Aggregation of the Alzheimer`s Disease Associated Aβ42 Peptide.

Bolognesi B, Cohen SI, Aran Terol P, Esbjörner EK, Giorgetti S, Mossuto MF, Natalello A, Brorsson AC, Knowles TP, Dobson CM, Luheshi LM.

ACS Chem Biol. 2013 Nov 25.